|
Symbol Name ID |
Umod
uromodulin MGI:102674 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Proteinuria |
Focal segmental glomerulosclerosis |
Renal tubular atrophy |
Tubulointerstitial fibrosis |
Hyperechogenic kidneys |
Abnormal renal insterstitial morphology |
Renal hypoplasia |
Decreased glomerular filtration rate |
Nephritis |
Nephropathy |
Renal insufficiency |
Chronic kidney disease |
Impaired renal concentrating ability |
| Disease(s) Associated with UMOD | |||||||||||||
| familial juvenile hyperuricemic nephropathy |
| Mouse Phenotypes | renal/urinary system phenotype |
increased kidney apoptosis |
renal tubular necrosis |
increased kidney cell proliferation |
kidney corticomedullary cyst |
renal glomerulus cyst |
decreased urine creatinine level |
increased urine creatinine level |
increased urine ammonia level |
increased urine chloride ion level |
increased urine potassium level |
decreased urine sodium level |
increased urine sodium level |
abnormal urine organic anion level |
decreased urine citrate level |
abnormal urine homeostasis |
increased urine calcium level |
increased urine magnesium level |
abnormal urine osmolality |
decreased urine osmolality |
decreased urine pH |
increased urine phosphate level |
decreased urine protein level |
abnormal urine urea nitrogen level |
decreased urine uric acid level |
increased urine uric acid level |
crystalluria |
kidney inflammation |
abnormal kidney morphology |
abnormal papillary duct morphology |
dilated kidney collecting duct |
abnormal juxtaglomerular apparatus morphology |
dilated renal glomerular capsule |
glomerulosclerosis |
renal interstitial fibrosis |
abnormal kidney papilla morphology |
hydronephrosis |
decreased kidney weight |
renal tubule atrophy |
abnormal renal tubule morphology |
abnormal loop of Henle ascending limb thick segment morphology |
abnormal proximal convoluted tubule morphology |
dilated renal tubule |
renal cast |
nephrocalcinosis |
renal fibrosis |
urolithiasis |
abnormal renal/urinary system physiology |
decreased creatinine clearance |
increased creatinine clearance |
decreased renal glomerular filtration rate |
increased renal glomerular filtration rate |
isosthenuria |
kidney failure |
decreased urine flow rate |
increased urine flow rate |
polyuria |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Umodtm1.1Rvt/Umodtm1.1Rvt | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Umodtm1Kuma/Umodtm1Kuma | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Umodtm1Xrw/Umodtm1Xrw | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| UmodUrehd1/UmodUrehd1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Umodurehr4/Umodurehr4 | * | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Umodem1Duf/Umod+ | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Umodtm1.1Rvt/Umod+ | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Umodtm1Xrw/Umod+ | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| UmodUrehd1/Umod+ | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Umodurehr4/Umod+ | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Tg(Umod*C147W)958Lura/0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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